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N-Desethylsunitinib hydrochloride

CAS No. 1261432-05-6

N-Desethylsunitinib hydrochloride( —— )

Catalog No. M23434 CAS No. 1261432-05-6

N-Desethylsunitinib hydrochloride is a major and pharmacologically active metabolite of sunitinib, which is potent, ATP-competitive VEGFR, PDGFRβ, and KIT inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    N-Desethylsunitinib hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    N-Desethylsunitinib hydrochloride is a major and pharmacologically active metabolite of sunitinib, which is potent, ATP-competitive VEGFR, PDGFRβ, and KIT inhibitor.
  • Description
    N-Desethylsunitinib hydrochloride is a major and pharmacologically active metabolite of sunitinib, which is potent, ATP-competitive VEGFR, PDGFRβ, and KIT inhibitor.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    c-Kit
  • Recptor
    KIT|PDGFRβ|VEGFR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1261432-05-6
  • Formula Weight
    406.88
  • Molecular Formula
    C20H24ClFN4O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    O=C1C(C2=CC(F)=CC=C2N1)=CC(NC(C)=C3C(NCCNCC)=O)=C3C.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Determination of Sunitinib and Its Active Metabolite N-Desethylsunitinib in Sweat of a Patient.[J]. Journal of Analytical Toxicology, 2011.
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